Correlation between Transabdominal Sonographic and Clinical Findings in Children with Sickle Cell Disease

Pam S. Daniel, E. Gyang, A.E. Gabkwet, P.M. Gwom, E.O. Igoh, Y.F. Taiwo, A.J. Salaam, S.M. Danjem

Abstract


Background: Sickle cell disease (SCD) is a major cause of morbidity and mortality in Sub-Saharan Africa where intraabdominal manifestations of the disease are common. Objective: To correlate transabdominal sonographic and clinical findings in children with sickle cell disease. Materials and Methods: A cross-sectional study of 400 SCD patients aged 1-15 years, conducted in the Radiology department of Jos University Teaching Hospital. Patients were scanned using Aloka 3500 Ultrasound machine with frequency transducer range 2-10MHz. The patient lies supine and a hypoallergic gel is applied over the abdomen and the intra-abdominal organs are then scanned and their measurement/morphology are then documented. Results: Normal sonographic findings were seen in 192 (48.0%) patients while 208 (52.0%) had various abnormal findings. Two hundred and ninety-seven (74.2%) patients had various clinical abdominal presentations while 103 (25.8%) had none. The commonest abnormal transabdominal ultrasonographic (TAUS) finding was hepatomegaly seen in 120 (25.2%) patients, autosplenectomy seen in 77 (16.2%) and hyposplenism seen in 5 (1.1%). Higher abnormal TAUS findings were noted in the older age groups 11-15 years with 69 (85.2%). Patients who had a history of blood transfusion had significant abnormal TAUS findings (p-0.001). Conclusion: Abdominal ultrasonographic imaging of patients with sickle cell disease revealed various abdominal abnormalities.

Keywords: Sickle Cell Disease, Ultrasonographic, Transabdominal


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Copyright (c) 2021 Pam S. Daniel, E. Gyang, A.E. Gabkwet, P.M. Gwom, E.O. Igoh, Y.F. Taiwo, A.J. Salaam, S.M. Danjem

Copyright CC BY © European Modern Studies Journal 2017-2021   ISSN 2522-9400

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