Correlation between Central Corneal Thickness, Axial Length and Relative Lens Position with the Degree of Myopia in University of Sumatera Utara General Hospital and Affiliation Hospitals in Medan
AbstractIntroduction: The prevalence of myopia has constantly increased in recent decades, indicating serious public health problems. Myopia has increased the risk of visual impairment globally. Purpose: This study aims to analyze the correlation between central corneal thickness, axial length, and relative position with the degree of myopia in University of Sumatera Utara General Hospital and affiliation hospitals in Medan. Materials and Methods: This study was an observational analytical study with cross-sectional design. Inclusion criteria were myopia patients with minimal age of 18 years old, myopia with spherical equivalent 0.25 or less, and agreed to participate in this study. Exclusion criteria were best corrected visual acuity less than 6/6, patients with systemic and ocular diseases, patients with unclear refractive media, patients with a history of ocular surgery. The measurements of this study were refraction status, central corneal thickness by pachymetry, ocular biometry by A-scan USG, and relative lens position. Data were analyzed using Kruskal-Wallis test, One Way ANOVA, and Bonferroni. Result: A total of 70 eyes from 35 myopia patients were included in this study, most were female (54.3%). Mean age was 24.6±4.48 years. In this study, mean central corneal thickness was 525.97±27.22 µm, mean axial length was 24.65 mm±1.62 mm, and mean relative lens position was 2.01±0.18 µm. Most patients had lower myopia degree. There was a significant correlation between central corneal thickness and myopia degree in all subjects. There was a significant correlation between axial length and myopia degree in all subjects. There was a significant correlation between the relative lens position and myopia degree. Conclusion: There was a correlation between the degree of myopia with the central corneal thickness, axial length, and relative lens position.
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