Coronaviral Disease 2019 (COVID-19) and Pregnancy: Motheral Outcomes and Clinical Progression

  • Khalida Sharipova
  • Gulnur Sekerbay
  • Nauryzgul Kenebaeva
  • Zhuldyz Koshkimbaeva


Abstract. The impact of coronavirus infection (SARS-CoV-2) on pregnant women is still poorly understood; the present data indicate a varying progression of the disease from asymptomatic to manifest forms. The question arises, whether the incidence of coronavirus disease (COVID-19) can complicate the course and affect the outcome of pregnancy.Research goal. To study the clinical course and pregnancy outcome associated with coronavirus infection (SARS-CoV-2).Material and methods. The retrospective study of the medical case histories of pregnant women with PCR confirmed coronavirus infection (SARS-CoV-2) was carried out at the perinatal center "Multipurpose city hospital No. 3" in Nur-Sultan. During the time of COVID high incidence in the city of Nur-Sultan, 68 case histories of pregnant women were analyzed and 45 women in childbirth were selected for the period from June to August 2020.Results and discussion. Pregnant patients with a positive result of coronavirus infection n = 45, whose age ranges from 21 to 42 years, with a mean of 30 years. Asymptomatic course of coronavirus disease in puerperas, 71% (n = 32) and symptomatic course with varying severity, 29% (n = 13). Diagnostics of obstetric patients (puerperas) with symptomatic course of COVID-19 by X-ray and CT-100% (n = 13), most have symptoms of 2-sided pneumonia 69% (n = 9), and chronic bronchitis 31% (n = 4). All obstetric patients (puerperas with symptomatic course of coronavirus disease (COVID-19) - 29% (n = 13) had metabolic syndrome with varying degrees of obesity.Conclusion. Most patients with laboratory confirmed infection (SARS-CoV-2) admitted to childbirth were asymptomatic for COVID-19. Almost a third of patients who had symptoms and complications of this disease on admission had varying degrees of obesity. Thus, it can be concluded that maternal obesity is one of the most serious comorbidities associated with a more severe course of coronavirus disease. In general, pregnancy is not a significant risk factor for developing severe coronavirus disease (COVID-19).Key words: coronavirus disease (COVID-19), obesity, overweight, pregnancy, extragenital diseases