The Effect of Purple Eggplant Extract Administration on the Number, Motility, and Vitality of Spermatozoa in Male Sprague Dawley Rats
AbstractBackground: Rapid and low-quality population growth will become a burden for development which makes it difficult for the government to fulfill basic human rights such as education, health, and employment for the people. Without any efforts of intensive prevention, humans will be trapped in poverty and ignorance. There are only two types of effective male contraceptives or also known as male birth control in the world namely condoms and vasectomy so that more varied male contraceptives are necessary. Purple eggplant has been studied and has a benefit for antifertility.Objectives: To determine the effect of purple eggplant extract in reducing the number, motility, and vitality of spermatozoa in male Sprague Dawley rats.Method: This study used the Randomized Post Test Only Control Trial design. The research population was 28 male Sprague Dawley rats aged 3 months weighing 200-250 grams and were divided into four groups: control group, the first group with a dose of 10 mg/kg body weight, the second group with a dose of 10 mg/kg body weight, the second group with a dose of 50 mg/kg body weight, the third group with a dose of 50 mg/kg body weight.Results: The results of the ANOVA test for the mean number or the average of the numbers of spermatozoa cells in the treatment group obtained a value of P = 0.362 (Ρ> 0.05) so that it can be concluded that there is no significant difference in the mean number of spermatozoa cells between the three treatment groups. The results of the Kruskal Wallis test analysis for the mean number of spermatozoa motility in the treatment group obtained f count 8.647 with a value of Ρ = 0.034 (Ρ <0.05) so that it can be concluded that there is a significant difference in the mean number of spermatozoa motility between the four treatment groups. One-way ANOVA test in this study found f = 8.836 with a value of Ρ = 0.012 (P <0.05) and therefore it can be concluded that there is a significant difference in the spermatozoa vitality between the four treatment groups.Conclusion: There is an effect of purple eggplant extract administration in reducing the number, motility, and vitality of spermatozoa in male Sprague Dawley rats.Keywords: Purple eggplant extract, number of spermatozoa, spermatozoa motility, and spermatozoa vitality
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