Correlation between 25-Hydroxy Vitamin D Serum Levels with Contrast Sensitivity, Color Vision and Visual Fields in Moderate-High Myopia
Abstract
Background: Myopia is a visual impairment problem that constantly increases, causing public health problems and economic burdens globally. Previous studies have shown that vitamin D deficiency is associated with decreased visual acuity as well as visual function. Objective: To determine the correlation between 25-hydroxy vitamin D serum levels with contrast sensitivity, color vision, and visual fields in moderate-high myopia. Methods: This study was an observational analytic study with a cross-sectional design. Visual function tests performed were visual acuity test, Pelli-Robson contrast sensitivity chart, pseudoisochromatic Ishihara, Humphrey visual field analyzer, and ELISA test for 25(OH)D. Results: The sample of this study was 50 subjects with moderate to high myopia consisting of 39 females (60%) with a mean age of 26.62±3.70 years. The distribution of moderate myopia and high myopia was 30% and 20% with a mean spherical equivalent of -5.11±1.54 D. Spearman correlation analysis found no statistically significant correlation between serum 25(OH)D and contrast sensitivity (p=0.132, r=0.216). Color vision was homogeneous in all patients, Fischer's exact analysis of the visual field in the right eye (p=0.001), and in the left eye (p=0.132). Subjects with vitamin D deficiency were 24 patients (48%), and with vitamin D insufficiency was 1 subject (2%), with an average level of 25(OH)D 44.56±41.45 ng/ml. Conclusions: Serum levels of 25-hydroxy vitamin D were not correlated to contrast sensitivity and color vision. However, a significant correlation between 25-hydroxy vitamin D serum levels with the visual field in one eye was found.Terms and conditions of Creative Commons Attribution 4.0 International License apply to all published manuscripts. This Journal is licensed under a Creative Commons Attribution 4.0 International License. This licence allows authors to use all articles, data sets, graphics and appendices in data mining applications, search engines, web sites, blogs and other platforms by providing appropriate reference. The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
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